<b>SIGNAL TRANSDUCTION MACHINERY OF THE PARIETAL CELL SECRETORY </b><b>SYSTEM </b>
نویسندگان
چکیده
منابع مشابه
Discussion: Parietal Cell Secretory Regulation
The maladies of gastric secretion, including peptic ulcer disease, gastritis, and esophageal reflux, represent common and pervasive disorders throughout our population. Investigations during the past two decades have led to remarkable and profound changes in the treatment of acid-peptic disorders. Medical treatments have evolved from gastric resection through the evolution of "physiological" an...
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PHYSIOLOGISTS GENERALLY ACCEPT the H -K -ATPase as the principal gastric proton pump, and a mechanism of membrane recruitment and recycling of the pump as the primary means for regulating the activity of gastric HCl secretion. One of the major challenges in gastric HCl secretory physiology is the identification and characterization of the K efflux pathway across the apical membrane that must ac...
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Secretion and membrane fusion are fundamental cellular processes regulating endoplasmic reticulum (ER)–Golgi transport, plasma membrane recycling, cell division, sexual reproduction, acid secretion, and the release of enzymes, hormones, and neurotransmitters, to name just a few. It is therefore no surprise that defects in secretion and membrane fusion give rise to diseases such as diabetes, Alz...
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Natural killer (NK) cells and cytotoxic T lymphocytes eliminate virally infected and transformed cells. Target cell killing is mediated by the regulated exocytosis of secretory lysosomes, which deliver perforin and proapoptotic granzymes to the infected or transformed cell. Yet despite the central role that secretory lysosome exocytosis plays in the immune response to viruses and tumors, little...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1996
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.17.403